Dermavant to Present New ADORING Data on VTAMA® Cream for Atopic Dermatitis at 2024 AAD Meeting

Dermavant Sciences to Present New ADORING Data on Tapinarof Cream for Atopic Dermatitis at 2024 AAD Annual Meeting

Dermavant Sciences, a biopharmaceutical company specializing in innovative therapies for immuno-dermatology, will unveil new ADORING data at the 2024 American Academy of Dermatology Annual Meeting. The data includes the treatment of patients with skin of color from Phase 3 trials of VTAMA® (tapinarof) cream, 1%, in adults and children aged 2 years and older with atopic dermatitis. This event will be held from March 8-12 in San Diego, California.

The VTAMA cream, an aryl hydrocarbon receptor agonist, is being developed as a once-daily, cosmetically elegant, and steroid-free topical cream for both acute treatment and long-term management of atopic dermatitis (AD). VTAMA cream, 1%, has current approval for the topical treatment of plaque psoriasis in adults in the U.S. and is the same strength and formulation under study in the ADORING Phase 3 development program for AD.

Several oral and poster presentations will be featured, highlighting key aspects of the ADORING trials:

  1. Tapinarof Cream 1% Once Daily in Adults and Children Down to 2 Years of Age with Moderate to Severe Atopic Dermatitis in Two Phase 3 Trials: Patient-reported Outcomes
    • Presenter: Eric Simpson, MD, MCR
    • This presentation will focus on patient-reported outcomes (PROs) including quality of life measures and assessment of AD symptoms for adults and children treated with tapinarof cream 1% once daily from the Phase 3 ADORING trials.
  2. Tapinarof Cream 1% Once Daily: Interim Analysis of ADORING 3 Phase 3 Long-term Extension Trial in Adults and Children Down to 2 Years of Age with Atopic Dermatitis
    • Presenter: Robert Bissonnette, MD
    • This presentation will include data on the baseline characteristics of patients enrolling in ADORING 3, an open-label, long-term extension trial assessing the safety and efficacy of tapinarof cream 1% once daily for up to 48 weeks in adults and children with AD.

Additionally, two posters will present data on the efficacy and safety of tapinarof cream 1% once daily in adults and children with AD, focusing on patients with skin of color and the treatment’s tolerability across two pivotal Phase 3 trials.

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