Inventia Life Science Unveils RASTRUM™ Allegro to Transform High-Throughput 3D Cell Culture in Drug Discovery and Disease Research
Inventia Life Science Unveils RASTRUM™ Allegro to Revolutionize High-Throughput 3D Cell Culture for Drug Discovery and Disease Research
Inventia Life Science, a leader in the field of 3D cell culture technologies, is proud to announce the launch of RASTRUM™ Allegro, a groundbreaking platform that promises to accelerate drug discovery and disease research with enhanced scalability, reproducibility, and efficiency. The platform addresses the critical needs of modern research, providing an innovative solution that allows for the creation of complex, biologically relevant 3D cell models with minimal hands-on time.
The Importance of Biologically Relevant Models in Research
“Scientists know the value of biologically relevant models for advancing their work,” said Julio Ribeiro, Founder and CEO of Inventia Life Science. Traditional 2D cell cultures, while widely used, often fail to accurately replicate the complexity of human biology. Researchers have long sought more advanced systems that can better mimic the complexities of tissues and diseases, enabling them to gain deeper insights and make more informed decisions.
RASTRUM Allegro is designed to address these needs by providing an easy-to-use, high-throughput 3D cell culture system. It allows researchers to create complex and reproducible 3D cell models that are more representative of human biology. This next-generation technology allows for the generation of 3D models at a scale and level of precision that were previously difficult to achieve.
Addressing Key Challenges in 3D Cell Culture
A major challenge in research has been the limited availability of patient-derived cells. These cells are often difficult to expand and maintain in traditional 3D culture environments. RASTRUM Allegro seeks to overcome this obstacle by enabling the efficient use of patient-derived cells, optimizing them for translational research applications. With its innovative design, the platform is able to generate more models from smaller cell samples, allowing researchers to make better use of limited biological material.
RASTRUM Allegro addresses the inherent challenges of maintaining consistent, scalable 3D models. The platform significantly reduces the complexity associated with traditional 3D cell culture systems, ensuring that scientists can generate high-quality, reproducible models with minimal effort. This streamlined approach frees up researchers’ time, enabling them to focus more on their research rather than on time-consuming technical details.
Empowering Researchers with Precision and Scalability
“RASTRUM Allegro was designed to give researchers the power to create complex 3D models that closely mimic human biology,” said Ribeiro. “The system provides the precision and scalability necessary to advance drug discovery and disease research.” Researchers can now generate high-throughput 3D cell culture assays at a fraction of the cost and time previously required.
One of the key advantages of RASTRUM Allegro is its ability to significantly reduce per-sample costs, making high-throughput experimentation more affordable. This reduction in cost enables researchers to explore a greater number of variables, leading to more comprehensive and insightful results. In addition, the platform ensures consistency across experiments, which is critical for generating reliable data.
RASTRUM Allegro’s efficiency also plays a pivotal role in drug discovery. By accelerating the process of creating 3D cell models, researchers can screen drug candidates more quickly and effectively. This speed, combined with the platform’s ability to maintain reproducibility and biological relevance, helps shorten the timeline for drug development and brings novel therapies to market faster.
A Technology Built on Inventia’s Vision for Biomedical Advancement
The development of RASTRUM Allegro is a testament to Inventia Life Science’s broader mission to revolutionize biomedical research. The company has long been committed to providing researchers with tools that offer reliable and scalable models of human disease, thereby advancing our understanding of biology. According to Ribeiro, “RASTRUM Allegro is a continuation of this mission—helping researchers unlock new biological insights while maintaining accessibility and affordability.”
RASTRUM Allegro builds on Inventia’s established technology platform and takes it to the next level by enhancing its scalability and efficiency. The new system is designed to make 3D cell culture more accessible to a wider range of researchers, from small labs to large pharmaceutical companies. By simplifying the process, Inventia hopes to foster innovation in drug discovery and disease research, empowering researchers to develop new treatments with greater confidence.
Transforming Drug Discovery Workflows
RASTRUM Allegro is already transforming how researchers approach drug screening Inventia and disease modeling. Cameron Ferris, PhD, COO of Inventia Life Science, explained that for years, scientists have faced a difficult decision between choosing biological complexity or scalability. “With RASTRUM Allegro, we’ve eliminated that Inventia trade-off. Now researchers can achieve high-throughput 3D cell culture without sacrificing reproducibility. The platform Inventia enables them to scale their experiments while maintaining high-quality results—something that was previously difficult to achieve.”
The new system’s ability to create complex disease models quickly and consistently is a game-changer for drug discovery. Researchers can now study a wider range of disease phenotypes, leading Inventia to a deeper understanding of disease mechanisms and more effective therapeutic strategies. This capability is particularly useful for screening drug candidates against a variety of diseases, including cancer, neurological disorders, and cardiovascular diseases.
Key Benefits of RASTRUM Allegro
RASTRUM Allegro offers a range of features that make it a powerful tool for researchers:
- Scalability and Speed: The platform is optimized for high-throughput experimentation, allowing researchers to generate 3D cell models quickly and efficiently. In just six minutes, researchers can create models on a 96-well plate, and in nine minutes, on a 384-well plate. With a throughput of over 35 plates per day, RASTRUM Allegro offers exceptional scalability for large-scale studies.
- Reproducibility: One of the biggest challenges in cell culture research is ensuring consistent, reproducible results. RASTRUM Allegro delivers high-quality, reproducible results Inventia with post-print coefficients of variation (CVs) of less than 10% and downstream assay CVs under 19%. This level of reproducibility is crucial for generating reliable data across different experiments and ensuring the success of drug discovery programs.
- Efficiency: The system is optimized for patient-derived samples, making it an ideal tool for translational research. Researchers can create up to 3.5 times more cell models from limited cell numbers, enabling more comprehensive studies with fewer samples.
- Affordability: One of the most significant advantages of RASTRUM Allegro is its cost-effectiveness. By lowering the cost per well, the platform makes 3D cell culture more accessible to researchers with varying budgets. This cost reduction is crucial in ensuring that advanced 3D models are available to a wider community of scientists.
