Pramana Partners with ARUP Laboratories to Digitize Pathology Slides and Develop AI Hematopathology Algorithms
Pramana, Inc., an AI-driven health tech company focused on transforming the pathology industry, has teamed up with ARUP Laboratories, the largest nonprofit clinical and academic reference laboratory in the U.S., to digitize pathology slides and develop AI-powered algorithms aimed at enhancing the evaluation of bone marrow biopsies and addressing critical diagnostic challenges in hematopathology. This collaboration merges ARUP’s expertise in hematopathology with Pramana’s innovative SpectralHT autonomous whole-slide imaging scanners, working together to improve diagnostic accuracy and efficiency.
Pramana, Inc., a leader in AI-powered health technology, has announced a strategic collaboration with ARUP Laboratories, the largest nonprofit clinical and academic reference laboratory in the U.S., to digitize pathology slides and create AI-driven algorithms for improving bone marrow biopsy assessment and addressing other diagnostic challenges in hematopathology. This partnership merges ARUP’s expertise in hematopathology with Pramana’s innovative SpectralHT autonomous whole-slide imaging scanners, advancing diagnostic precision and workflow efficiency.
“Hematopathology involves highly complex and difficult-to-scan specimens, where traditional methods often fall short in delivering consistent and reproducible results,” explained Dr. David Ng, the medical director of Hematologic Flow Cytometry and Applied Artificial Intelligence at ARUP Laboratories. “By combining our deep clinical expertise with Pramana’s large-scale digitization and AI-powered analysis, we can develop and clinically validate new AI algorithms that will improve diagnostic accuracy and workflow efficiency. Additionally, this collaboration paves the way for broad distribution of these AI tools, ensuring greater accessibility and impact across the pathology community.”
The AI model development process will be led by ARUP, utilizing its expert hematopathologists and annotation tools to train, refine, and validate the algorithms using real-world clinical cases and pathology slides. These algorithms will be designed to run efficiently on Pramana’s SpectralHT scanners, showcasing the viability of in-line edge computing for real-time AI-powered diagnostics. Both companies will also explore commercialization strategies to enable the seamless deployment of these advanced diagnostic algorithms, ensuring compliance with regulatory standards and facilitating broader adoption in clinical diagnostics.
“This partnership with ARUP Laboratories demonstrates how AI-driven pathology can redefine industry standards, making diagnostics more scalable, efficient, and interoperable,” said Prasanth Perugupalli, chief product officer at Pramana. “By leveraging edge computing, we’re accelerating the adoption of advanced diagnostic algorithms, including those for complex hematopathology cases. This approach enhances precision, removes scalability barriers, and seamlessly integrates AI-driven insights into lab workflows.”
Pramana’s SpectralHT scanners are equipped with in-line Edge AI computing, allowing real-time quality control and automated image processing. This capability streamlines the workflow, reducing the burden on lab personnel while ensuring high-quality data output. The scanners’ volumetric imaging capabilities improve image quality and detail, significantly enhancing scanning efficiency for challenging diagnostic slides, including those in microbiology, hematopathology, parasitology, and cytology.
The collaboration between ARUP Laboratories and Pramana represents a significant commitment to the digitization and advancement of AI-driven pathology, with the potential for deeper integration and expanded initiatives, including clinical applications. This partnership is a key step in transforming the diagnostic process for complex hematopathology cases and driving efficiencies in lab environments.
About Pramana, Inc.
Pramana, Inc. is an AI-powered health tech company focused on modernizing the pathology sector. The company helps pathology labs and medical centers seamlessly adopt digital solutions by providing AI-enabled decision support. Pramana is based in Cambridge, Massachusetts, and backed by Matrix Capital, a global leader in customized investment solutions, and NTTVC, a leading firm that backs diverse founders within the technology spectrum.
About ARUP Laboratories
Founded in 1984, ARUP Laboratories is a leading national reference laboratory and a nonprofit enterprise of the University of Utah’s Spencer Fox Eccles School of Medicine and its Department of Pathology. ARUP offers more than 3,000 tests and test combinations, ranging from routine screening tests to esoteric molecular and genetic assays. Additionally, ARUP is a worldwide leader in innovative laboratory research and development, led by the ARUP Institute for Research and Innovation in Diagnostic and Precision Medicine™. ARUP is ISO 15189 and CAP accredited.
