PHC to Showcase LiCellGrow Prototype for Automated Cell Culture at Regenerative Medicine JAPAN 2024
PHC Corporation’s Biomedical Division will present the prototype of “LiCellGrow,” an automated cell culture device designed for developing cell medicine manufacturing processes, at the Regenerative Medicine JAPAN 2024 event in Yokohama from October 9 to 11. This innovative device offers real-time visualization of metabolic changes in cells and automatically adjusts the culture conditions based on these measurements.
With the rise of cell gene therapy (CGT) as a promising treatment for previously hard-to-treat diseases, the demand for high-quality and safe cell medicines—including CAR-T therapies—has surged. The challenge lies in the variability of autologous cells, which can lead to inconsistent cell quality and increased manufacturing costs due to reliance on end-product sampling.
The LiCellGrow device aims to address these challenges by employing unique in-line monitoring technology to continuously measure glucose and lactate concentrations in the culture medium. This allows for real-time adjustments to optimize cell culture conditions, thereby enhancing cell quality, reducing production losses, and improving manufacturing efficiency. Additionally, the device features a single-use culture bag that minimizes contamination risks and supports a sterile environment.
LiCellGrow utilizes the same proprietary in-line monitoring technology featured in PHC’s recently launched LiCellMo live cell metabolic analyzer. By integrating advanced blood glucose sensor technology, it achieves precise, continuous measurements of metabolic substances in cell cultures.
PHC’s Biomedical Division has over 20 years of experience in cell therapy innovations, including the establishment of cell processing facilities and the development of specialized isolators. The company is committed to enhancing quality, cost, and delivery in therapeutic manufacturing, thereby facilitating the adoption of CGT.
Event Details:
- Dates: October 9-11, 2024
- Location: Pacifico Yokohama (PHCbi Booth No.: R-28)
