Mosaic Clinical Technologies™ Appoints Mike Peresie as President, Signaling Major Acceleration in Next-Generation Clinical Workflow Innovation
Mosaic Clinical Technologies™ (Mosaic), the technology and AI services division of Radiology Partners (RP), has announced a significant leadership expansion with the appointment of Mike Peresie as President. The move marks a pivotal milestone for the organization as it continues to scale its technology footprint, strengthen its AI-driven clinical workflow solutions, and expand its partnerships across hospitals and health systems nationwide.
Peresie—an accomplished digital health and technology executive—brings more than 20 years of leadership experience spanning high-growth innovation portfolios, enterprise-scale software operations, and complex network and data businesses. His work has centered on developing and commercializing technology platforms that advance healthcare transformation by enhancing quality, improving access, and optimizing affordability. Mosaic leaders described his appointment as a strategic step in accelerating the organization’s mission to build the operating system that powers the next generation of radiology and clinical workflow innovation.
Rich Whitney, CEO of both Mosaic and Radiology Partners, emphasized the importance of the appointment at this stage of Mosaic’s evolution. “Mike is an outstanding leader with an impressive track record of value creation,” Whitney said. “His experience building high-performing teams and scaling mission-critical technology businesses makes him the right leader to accelerate Mosaic’s growth and drive unique value to patients and Mosaic’s health system customers alike.”
A Leader with a Proven Record of Transforming Healthcare Technology
Before joining Mosaic, Peresie spent several years in senior executive roles at Optum Insight, one of the nation’s largest healthcare technology and analytics organizations. Most recently, he served as Chief Innovation Officer, where he oversaw an AI-first innovation portfolio focused on addressing some of the most persistent and impactful challenges in the U.S. healthcare system. His leadership centered on designing tools and systems that modernize clinical workflows, reduce administrative burden, enhance patient outcomes, and introduce automation into high-cost, high-complexity processes.
In an earlier role at Optum, Peresie served as CEO of the company’s Software, Network and Data business—an expansive, multi-billion-dollar portfolio that includes a wide array of technology solutions for healthcare providers, payors, pharmacies, and other stakeholders. Under his leadership, the business advanced key digital transformation initiatives, strengthened operational efficiency, and drove new levels of automation across administrative and clinical workflows. He was responsible for leading thousands of employees across technology, product, data science, operations, and customer engagement functions, and was widely recognized for building cohesive, high-performing teams.
Prior to these positions, Peresie held progressive leadership roles at Optum Insight and at Change Healthcare, one of the largest healthcare technology firms in the United States. He played a central role in the strategic expansion of Change Healthcare, including its high-profile IPO and subsequent merger with Optum—a complex integration that reshaped the competitive landscape in healthcare data, analytics, and technology. These experiences positioned him as a respected industry leader with deep insight into the operational, financial, and innovation levers that drive sustainable, long-term value in health technology.
Driving Mosaic’s Ambitious Vision for the Future of Clinical Workflows
As President of Mosaic Clinical Technologies, Peresie will lead all aspects of Mosaic’s technology and business strategy. His responsibilities will encompass product innovation, MosaicOS™ platform development, operations, regulatory compliance, AI advancement, customer success, marketing, and the organization’s go-to-market strategy. He will also be charged with scaling Mosaic’s suite of solutions, which are designed to support clinicians, enhance radiology workflow efficiency, expand system capacity, and improve patient care quality.
Mosaic’s flagship platform, MosaicOS™, has been rapidly gaining traction among hospitals and health systems that are seeking to modernize radiology operations, reduce burnout, increase throughput, and improve diagnostic consistency. Built with an emphasis on physician-AI collaboration, the platform integrates workflow orchestration, imaging operations, intelligent triage, AI-enabled quality support, and advanced reporting capabilities. These solutions help radiology groups and health systems address rising patient volumes, ongoing workforce shortages, and the increasing complexity of imaging demands.
Under Peresie’s leadership, Mosaic aims to accelerate its AI roadmap and introduce additional capabilities that support clinical decision-making, optimize operational performance, and bring more automation into traditionally manual processes. His experience overseeing large AI and data portfolios uniquely positions him to guide Mosaic’s strategy in an era where healthcare organizations are seeking scalable, reliable, and clinically validated AI systems.
A Turning Point for Radiology and Healthcare Technology
Peresie noted that the timing of his appointment aligns with a critical moment for radiology and the broader healthcare landscape. The field is experiencing rapid growth in imaging volume, increased diagnostic complexity, and significant staffing challenges. These pressures make the need for modern technology solutions more urgent than ever.
“I’m thrilled to join Mosaic Clinical Technologies™ at a pivotal moment for radiology,” Peresie said. “Mosaic has already demonstrated that modern technology thoughtfully built, with physician-AI collaboration at the forefront, can fundamentally change physician capacity, diagnostic accuracy and patient care. I look forward to building on this momentum and scaling solutions that improve outcomes and access across the healthcare system.”
His remarks highlight the growing consensus that successful healthcare innovation must balance advanced technology—particularly AI—with the expertise, judgment, and workflow needs of clinicians. Mosaic’s platform emphasizes that balance, ensuring AI tools are integrated seamlessly into the clinical environment rather than operating as standalone systems.
Strengthening Partnerships and Expanding National Impact
Mosaic’s technology has already been deployed across numerous hospitals and health systems, supporting radiology teams in their efforts to streamline workflow, reduce turnaround times, maintain diagnostic quality, and improve patient experience. The addition of Peresie is expected to deepen existing relationships while expanding Mosaic’s footprint in both existing and new markets.
Healthcare leaders across the industry are increasingly seeking partners capable of delivering comprehensive, enterprise-scale workflow solutions—particularly those that combine cloud technology, AI, analytics, and operational expertise. Mosaic’s alignment with Radiology Partners, the nation’s largest radiology practice, gives it access to expansive clinical data, large-scale real-world radiology operations, and continuous feedback from thousands of radiologists. This clinical-technology integration positions Mosaic uniquely in the marketplace.
Peresie’s background in managing and scaling complex enterprise systems is expected to accelerate Mosaic’s ability to meet rising demand and to expand the functionality and sophistication of its offerings. His leadership will also support Mosaic’s strategic initiatives in innovation, AI governance, product reliability, and regulatory readiness—critical areas as AI adoption continues to grow across clinical environments.
A Future Built on Innovation and Collaboration
With Peresie stepping into the role of President, Mosaic is poised for its next phase of growth. The organization plans to advance its platform capabilities, introduce new AI-driven tools that support radiologists and clinical teams, and strengthen operational integration across the health systems it serves. Mosaic will also continue investing in partnerships with clinicians to ensure that new innovations align with real-world workflow needs, quality standards, and patient outcomes.
The appointment underscores Mosaic’s commitment not only to building innovative technology but also to creating sustainable and scalable systems that help healthcare organizations deliver better and more efficient care. As radiology continues to serve as a backbone of diagnosis and patient management, Mosaic aims to redefine how imaging operations function and how technology can elevate the entire continuum of care.
Peresie’s leadership represents a bold step forward for Mosaic Clinical Technologies™, reinforcing its dedication to advancing healthcare through thoughtful, clinically informed, and scalable technology solutions. As the healthcare system increasingly turns to digital transformation to address longstanding challenges, Mosaic’s strategic expansion positions it to play a leading role in shaping the future of clinical workflows across the country.
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