
Wolters Kluwer Health Showcases UpToDate Expert AI and Workflow Innovations at HLTH 2025
Wolters Kluwer Health is set to highlight the next generation of clinical decision support with its UpToDate Expert AI at HLTH 2025. Attendees visiting booth #3218 will have the opportunity to explore live demonstrations of the recently launched UpToDate Expert AI, a solution designed to integrate responsible, evidence-based generative AI into healthcare workflows. By providing rapid, reliable clinical insights, UpToDate Expert AI aims to streamline decision-making for healthcare providers and empower organizations to enhance care delivery across the patient journey.
The solution is built on Wolters Kluwer’s deep clinical expertise and over a decade of AI experience, reflecting the company’s commitment to delivering trusted, accurate, and actionable insights. UpToDate Expert AI is designed not merely to generate fast responses, but to provide guidance grounded in peer-reviewed clinical evidence and vetted by expert contributors. In addition to Expert AI, Wolters Kluwer Health will showcase a range of innovative solutions aimed at unlocking value across the care continuum, reinforcing the organization’s dedication to transparency, trust, and workflow efficiency.
UpToDate Pro Plus: Bringing AI to Students and Clinicians
Alongside Expert AI, Wolters Kluwer Health recently announced the launch of UpToDate Pro Plus, which integrates Expert AI capabilities with the existing UpToDate Pro platform. This combination is designed to bring responsible generative AI to students, residents, and group practice clinicians, providing a tool that supports faster, smarter, and evidence-based decision-making. The platform leverages Wolters Kluwer’s proprietary AI framework and deep clinical knowledge to ensure that recommendations are credible and aligned with current standards of care.
Greg Samios, CEO of Wolters Kluwer Health, emphasized the importance of clinical reliability in AI-driven tools. “Our customers have made it clear that GenAI at the point-of-care must be grounded in clinical credibility and expert guidance—not just fast answers. UpToDate Expert AI is already being adopted by clinicians across 70% of our largest enterprise health systems, signaling strong momentum and trust in our approach,” he said. Samios further reinforced the company’s mission to deliver accurate, actionable information to the right person at the right time while maintaining transparency, trust, and seamless integration into clinical workflows.
UpToDate Expert AI currently draws on contributions from over 7,600 expert reviewers and authors, ensuring that every recommendation is vetted, evidence-based, and relevant to real-world clinical practice. The platform aims to deliver actionable insights both for individual clinicians and for entire health system enterprises, making it a versatile tool for improving patient outcomes and supporting healthcare decision-making at scale.
Generative AI in Healthcare: Trust, Speed, and Privacy
As part of HLTH 2025, Wolters Kluwer Health will host a session on generative AI and care delivery. On Tuesday, October 21, at 3:30 p.m. PDT in the HLTH AI Zone (Theater C), Dr. Amanda Heidemann and Dr. Holden K. Groves from New York-Presbyterian Hospital will present a session titled “Why Compromise on Trust? AI in Healthcare.” The presentation will focus on how generative AI in healthcare can balance the critical factors of reliability, speed, and privacy without requiring clinicians to compromise any of these pillars.
The session will explore how UpToDate Expert AI leverages generative AI capabilities while maintaining clinician oversight, rigorous evidence review, and expert validation. Attendees will learn how a trusted, clinician-driven approach can ensure that AI tools augment decision-making rather than replace the judgment of healthcare professionals. The session promises to offer practical insights into implementing generative AI responsibly and effectively in clinical environments.
Demonstrating AI-Enhanced Workflows Across Care Settings
Wolters Kluwer Health will showcase multiple demonstrations that illustrate how UpToDate Expert AI and associated tools can seamlessly integrate into clinicians’ existing workflows. These include:
- UpToDate patient education integrated into Epic workflows, allowing clinicians to provide evidence-based educational materials to patients directly within electronic health record systems.
- UpToDate Connect for digital health platforms, supporting care teams with AI-enhanced decision support across telehealth and remote care settings.
- UpToDate for retail pharmacies, demonstrating how pharmacists can leverage evidence-based AI tools for medication counseling and patient care.
- A collaboration with Abridge at booth #3032 to showcase AI-driven documentation and insights derived from clinical conversations.
- UpToDate with Dragon Copilot at the Microsoft booth (#3860), illustrating AI integration within speech recognition and clinical documentation workflows.
These demonstrations underscore Wolters Kluwer’s focus on delivering solutions that work where clinicians work, reducing friction and enhancing efficiency across care delivery environments.
Comprehensive Clinical Decision Support Portfolio
In addition to Expert AI, Wolters Kluwer will present its comprehensive suite of clinical decision support tools:
- UpToDate Enterprise Edition, offering enterprise-level analytics and insights for health systems.
- AI Enhanced Search and AI Enhanced Search – Mobile, enabling clinicians to find relevant information faster using AI-powered search capabilities.
- UpToDate Analytics Dashboard, providing actionable insights into clinical practice patterns and resource utilization.
- UpToDate Lexidrug and Medi-Span, which enhance medication management and safety by integrating AI insights with drug information and clinical guidance.
According to a recent report by Outsell, Inc., UpToDate Expert AI “raises the bar for clinical decision support, delivering trusted, transparent AI in real workflows.” The report notes that Wolters Kluwer’s approach is distinct from generic chatbots because it draws exclusively from UpToDate’s peer-reviewed, evidence-based content. Every response provided by Expert AI remains grounded in clinical evidence, offering transparency into the reasoning, assumptions, and sources behind each recommendation. This approach addresses a critical challenge in healthcare AI—avoiding “hallucinations” and ensuring that AI-driven guidance is both reliable and actionable.
Empowering Clinicians with Evidence-Based AI
The launch of UpToDate Expert AI and UpToDate Pro Plus reflects a broader trend in healthcare technology: the integration of AI into clinical decision-making while maintaining the highest standards of evidence and trust. By offering solutions that are clinician-validated and seamlessly embedded into workflows, Wolters Kluwer Health is supporting healthcare organizations in improving efficiency, accuracy, and patient outcomes.
For clinicians and health systems, the ability to access AI-enhanced insights in real-time can significantly reduce the time spent searching for information, allow for more precise decision-making, and ultimately contribute to improved patient care. The tools offered by Wolters Kluwer Health are designed to complement the expertise of healthcare professionals, providing support without replacing human judgment.
Scheduling Demonstrations at HLTH 2025
HLTH 2025 attendees interested in seeing these innovations firsthand can schedule individual briefings or demonstrations at Wolters Kluwer Health’s booth (#3218). The sessions will allow participants to explore the full capabilities of UpToDate Expert AI, UpToDate Pro Plus, and other integrated solutions. Demonstrations will highlight how generative AI can be applied responsibly across multiple care settings, from hospitals and retail pharmacies to digital health platforms and enterprise systems.




