At the ISPOR Europe 2024 Conference, CapeStart, Inc. unveiled MadeAi™, a generative AI-powered platform designed to revolutionize the synthesis of clinical information. The platform’s first solution, MadeAi-LR, enhances the efficiency of systematic literature reviews (SLRs), clinical evidence reports (CERs), meta-research, targeted literature reviews (TLRs), and other clinical literature assessments, significantly streamlining these complex processes.
For years, traditional literature reviews in life sciences have been labor-intensive and time-consuming, often diverting experts from higher-value tasks. CapeStart aims to change this with MadeAi-LR, a generative AI-powered solution that significantly streamlines the literature review process. By optimizing efficiency with near 90% accuracy for title and abstract screening, and over 80% accuracy for data extraction and article summarization, MadeAi-LR slashes the time spent on literature reviews by nearly half.
Developed in collaboration with top 20 pharmaceutical companies, MadeAi-LR centralizes and simplifies the review process, enabling teams to focus on more complex, high-impact work. The platform supports systematic literature reviews (SLRs), clinical evidence reports (CERs), meta-research, and more, improving productivity, ensuring more rigorous regulatory submissions, and facilitating better-informed internal strategies. With some literature reviews requiring hundreds of hours to complete, MadeAi-LR is helping pharma, biotech, and medical device companies save valuable time, optimize resources, and scale research to drive innovation.
“PhD researchers and life science experts should focus on breakthroughs in health, not on mundane tasks that can be handled with high accuracy by AI,” said Gaugarin Oliver, Founder and CEO of CapeStart. “MadeAi-LR enables faster, more efficient literature reviews, unlocking scalability and immediate ROI in both time and resources. We are committed to continuously improving the MadeAi platform to bring more value to life science innovation.”
GenAI-Powered and Expert-Verified
MadeAi, the platform powering MadeAi-LR, forms the foundation for CapeStart’s broader AI services. Future offerings will include tools for pharmacovigilance, clinical content generation, and global value dossier development.
Leveraging nearly a decade of AI expertise and deep clinical understanding, MadeAi-LR ensures compliance with FDA and EMA guidelines for SLR submissions. The platform features a central repository that provides stakeholders with visibility into every step of the workflow, enhancing transparency around included and excluded materials. The platform uses a human-in-the-loop (HITL) approach, combining AI innovation with expert verification to turn a traditionally tedious task into a highly accurate, productivity-enhancing process.
Transforming Literature Review into a Productivity Engine
MadeAi-LR offers a suite of features designed to free up researchers’ time for more strategic tasks:
- Centralized Collaboration Platform: Streamlines the end-to-end literature review process with full visibility for oversight throughout.
- Smart Search: Combines multiple databases (e.g., PubMed) into a unified search interface, providing a comprehensive view for researchers.
- GenAI-Aided Screening & Summarization: Automates article screening, single- and multi-article summarizations, and authoring, helping researchers quickly assess and process relevant data.
- Data Extraction: Semi-automated extraction assists in pulling key data from studies, with pinpointed references to the original sources.
- Confidence Scoring: Each article’s inclusion or exclusion is accompanied by a confidence score and detailed reasoning, ensuring expert validation and transparency.
- Full-Text Management: Direct integration with RightFind for easy access to full-text articles without navigating external sources.
- Compliance Checking: Built-in templates ensure PRISMA compliance, boosting credibility and trust in findings.
- Living Literature Review: Automatically updates completed reviews with new relevant articles matching predefined keywords.
- AI Services Expertise: Access to CapeStart’s team of experts to help clients optimize their use of the platform.
- Subject Matter Expertise: Optional services for expert medical writing and research support to bridge resource gaps.
MadeAi-LR has already garnered recognition, winning a Stevie® Award at the 21st Annual International Business Awards® for its innovation in AI/ML solutions for healthcare.
About CapeStart
CapeStart helps organizations thrive in the AI-driven economy, delivering innovative AI solutions across life sciences, healthcare, finance, and retail. Specializing in data annotation, machine learning model development, and software development, CapeStart’s platform combines AI efficiency with human oversight to help life science firms optimize resources and accelerate research. Based in Cambridge, MA, CapeStart serves over 100 clients with a global team of 600+ experts across North America, the Middle East, and Asia.
