Bio-Rad Reports First-Quarter 2023 Financial Results

 Bio-Rad Laboratories, Inc. (NYSE: BIO and BIOb), a global leader in life science research and clinical diagnostic products, today announced financial results for the first quarter ended March 31, 2023.

First-quarter 2023 net sales were $676.8 million, a decrease of 3.3 percent compared to $700.1 million reported for the first quarter of 2022. On a currency-neutral basis, quarterly sales decreased 0.3 percent compared to the same period in 2022. COVID-related sales were $2.6 million in the first quarter of 2023 versus approximately $45 million in the year ago period. Excluding COVID-related sales, revenue increased 6.1 percent on a currency-neutral basis.

Life Science segment net sales for the first quarter were $323.6 million, a decrease of 6.8 percent compared to the same period in 2022. On a currency-neutral basis, Life Science segment sales decreased by 3.6 percent compared to the same quarter in 2022. Excluding COVID-related sales, Life Science revenue grew 9.6 percent and was primarily driven by qPCR, western blotting, and Droplet Digital™ PCR products.

Clinical Diagnostics segment net sales for the first quarter were $352.1 million, or essentially flat when compared to the same period in 2022. On a currency-neutral basis, net sales increased 2.8 percent versus the same quarter last year. Excluding COVID-related sales, Clinical Diagnostics revenue increased 3.1 percent year over year, on a currency-neutral basis, driven by strong demand for diagnostic instruments.

First-quarter gross margin was 53.5 percent compared to 57.5 percent during the first quarter of 2022.

Income from operations during the first quarter of 2023 was $61.9 million versus $146.4 million during the same quarter last year.

Net income for the first quarter of 2023 was $69 million, or $2.32 per share, on a diluted basis, versus a net loss of $3,367 million, or $112.50 per share, on a diluted basis, during the same period in 2022. Net income (loss) amounts for the first quarter of 2023 and 2022 were primarily impacted by the recognition of changes in the fair market value of equity securities related to the holdings of the company’s investment in Sartorius AG.

The effective tax rate for the first quarter of 2023 was 18.7 percent, compared to 22.9 percent for the same period in 2022. The effective tax rate reported in Q1 2023 was primarily affected by geographical mix of earnings. The effective tax rate reported in Q1 of 2022 was primarily affected by an unrealized loss in equity securities.

“The expected decline in first quarter COVID-related sales resulted in lower year-over-year total revenues; however, we are encouraged by continued underlying strength of our core business in Life Science and Clinical Diagnostics,” said Norman Schwartz, Bio-Rad’s President and Chief Executive Officer. “While lingering effects of supply chain challenges continued to impact our operations during the quarter, we are working diligently through our elevated order backlog to meet customer demand.”

The non-GAAP financial measures discussed below exclude certain items detailed later in this press release under the heading “Use of Non-GAAP and Currency-Neutral Reporting.” A reconciliation between historical GAAP operating results and non-GAAP operating results is provided following the financial statements that are part of this press release.

Non-GAAP gross margin was 54.2 percent for the first quarter of 2023 compared to 58.2 percent during the first quarter of 2022.

Non-GAAP income from operations during the first quarter of 2023 was $84.2 million versus $156.8 million during the comparable prior-year period.

Non-GAAP net income for the first quarter of 2023 was $99.4 million, or $3.34 per share, on a diluted basis, compared to $151.5 million, or $5.02 per share, on a diluted basis, during the same period in 2022.

The non-GAAP effective tax rate for the first quarter of 2023 was 20.9 percent, compared to 19.6 percent for the same period in 2022. The higher rate in 2023 was driven by geographical mix of earnings and lower compensation-related deductions.

GAAP Results
 Q1 2023Q1 2022
Revenue (millions)$676.8$700.1
Gross margin53.5%57.5%
Operating margin9.1%20.9%
Net income (loss) (millions)$69.0($3,367.3)
Income (loss) per diluted share$2.32($112.50)
 
Non-GAAP Results
 Q1 2023Q1 2022
Revenue (millions)$676.8$700.1
Gross margin54.2%58.2%
Operating margin12.4%22.4%
Net income (millions)$99.4$151.5
Income per diluted share$3.34$5.02

A reconciliation between historical GAAP operating results and non-GAAP operating results is provided following the financial statements that are part of this press release. We do not provide a reconciliation of our non-GAAP financial expectations to expectations for the most comparable GAAP measure because the amount and timing of many future charges that impact these measures (such as amortization of future acquisition-related intangible assets, future acquisition-related expenses and benefits, future restructuring charges, future asset impairment charges, future valuation changes of equity-owned securities, future gains and losses on equity -method investments or future legal charges or benefits), which could be material, are variable, uncertain, or out of our control and therefore cannot be reasonably predicted without unreasonable effort, if at all.

Updated 2023 Financial Outlook

Bio-Rad is updating its financial outlook for full-year 2023. The company currently anticipates non-GAAP currency-neutral revenue growth of approximately 4.5 percent in 2023 compared to its previous estimate of 6.0 to 7.0 percent and an estimated non-GAAP operating margin of approximately 17.5 percent versus the company’s prior estimate of approximately 19.5 percent. Excluding COVID-related sales, Bio-Rad estimates full-year 2023 non-GAAP currency-neutral revenue growth to be approximately 8.5 percent versus its prior guidance of 10.0 to 11.0 percent.

Updated 2025 Financial Outlook

Bio-Rad is also updating its financial outlook for full-year 2025 presented at the company’s 2022 Investor Day event on February 25, 2022. The company now targets a currency-neutral, compounded annual average core revenue growth rate of approximately 8.0 percent between 2021 and 2025 versus its previous target of approximately 8.9 percent and an adjusted EBITDA margin of approximately 26.0 percent in 2025 compared to the company’s previous target of approximately 28.0 percent. Core revenue is defined as currency-neutral, non-GAAP revenue that also excludes COVID-related sales.

Conference Call and Webcast

Management will discuss the company’s first quarter ended March 31, 2023, results and financial outlook in a conference call at 2 PM Pacific Time (5 PM Eastern Time) on May 4, 2023. To participate, dial 833-470-1428 within the U.S. or +1 929-526-1599 outside the U.S., access code: 522530. A live webcast of the conference call will also be available in the “Investor Relations” section of the company’s website under “Events & Presentations” at investors.bio-rad.com. A replay of the webcast will be available for up to a year.

Use of Non-GAAP and Currency-Neutral Reporting

In addition to the financial measures prepared in accordance with generally accepted accounting principles (GAAP), we use certain non-GAAP financial measures, including non-GAAP net income and non-GAAP EPS, which exclude amortization of acquisition-related intangible assets, certain acquisition-related expenses and benefits, restructuring charges, asset impairment charges, gains and losses from change in fair market value of equity securities and loan receivable, gains and losses on equity-method investments, and significant legal-related charges or benefits and associated legal costs. Non-GAAP net income and non-GAAP EPS also exclude certain other gains and losses that are either isolated or cannot be expected to occur again with any predictability, tax provisions/benefits related to the previous items, and significant discrete tax events. We exclude the above items because they are outside of our normal operations and/or, in certain cases, are difficult to forecast accurately for future periods.

We utilize a number of different financial measures, both GAAP and non-GAAP, in analyzing and assessing the overall performance of our business, in making operating decisions, forecasting and planning for future periods, and determining payments under compensation programs. We consider the use of the non-GAAP measures to be helpful in assessing the performance of the ongoing operation of our business. We believe that disclosing non-GAAP financial measures provides useful supplemental data that, while not a substitute for financial measures prepared in accordance with GAAP, allows for greater transparency in the review of our financial and operational performance. We also believe that disclosing non-GAAP financial measures provides useful information to investors and others in understanding and evaluating our operating results and future prospects in the same manner as management and in comparing financial results across accounting periods and to those of peer companies. More specifically, management adjusts for the excluded items for the following reasons:

Amortization of purchased intangible assets: we do not acquire businesses and assets on a predictable cycle. The amount of purchase price allocated to purchased intangible assets and the term of amortization can vary significantly and are unique to each acquisition or purchase. We believe that excluding amortization of purchased intangible assets allows the users of our financial statements to better review and understand the historic and current results of our operations, and also facilitates comparisons to peer companies.

Acquisition-related expenses and benefits: we incur expenses or benefits with respect to certain items associated with our acquisitions, such as transaction costs, professional fees for assistance with the transaction; valuation or integration costs; changes in the fair value of contingent consideration, gain or loss on settlement of pre-existing relationships with the acquired entity; or adjustments to purchase price. We exclude such expenses or benefits as they are related to acquisitions and have no direct correlation to the operation of our on-going business.

Restructuring, impairment charges, and gains and losses from change in fair market value of equity securities and loan receivable, and gains and losses on equity-method investments: we incur restructuring and impairment charges on individual or groups of employed assets and charges and benefits arising from gains and losses from change in fair market value of equity securities and loan receivable, and gains and losses (including impairments) on equity-method investments, which arise from unforeseen circumstances and/or often occur outside of the ordinary course of our on-going business. Although these events are reflected in our GAAP financials, these unique transactions may limit the comparability of our on-going operations with prior and future periods.

Significant litigation charges or benefits and legal costs: we may incur charges or benefits as well as legal costs in connection with litigation and other contingencies unrelated to our core operations. We exclude these charges or benefits, when significant, as well as legal costs associated with significant legal matters, because we do not believe they are reflective of on-going business and operating results.

Income tax expense: we estimate the tax effect of the excluded items identified above to determine a non-GAAP annual effective tax rate applied to the pretax amount in order to calculate the non-GAAP provision for income taxes. We also adjust for items for which the nature and/or tax jurisdiction requires the application of a specific tax rate or treatment.

From time to time in the future, there may be other items excluded if we believe that doing so is consistent with the goal of providing useful information to investors and management.

Percentage sales growth in currency neutral amounts are calculated by translating prior period sales in each local currency using the current period’s monthly average foreign exchange rates for that currency and comparing that to current period sales.

There are limitations in using non-GAAP financial measures because the non-GAAP financial measures are not prepared in accordance with generally accepted accounting principles and may be different from non-GAAP financial measures used by other companies. The non-GAAP financial measures are limited in value because they exclude certain items that may have a material impact on our reported financial results. The presentation of this additional information is not meant to be considered in isolation or as a substitute for the directly comparable financial measures prepared in accordance with GAAP in the United States. Investors should review the reconciliation of the non-GAAP financial measures to their most directly comparable GAAP financial measures as provided in the tables accompanying this press release.

BIO-RAD and DROPLET DIGITAL PCR are trademarks of Bio-Rad Laboratories, Inc. in certain jurisdictions.

About Bio-Rad

Bio-Rad Laboratories, Inc. (NYSE: BIO and BIOb) is a global leader in developing, manufacturing, and marketing a broad range of innovative products for the life science research and clinical diagnostics markets. With focus on quality and customer service for over 70 years, our products advance scientific discovery and improve healthcare. Our customers are university and research institutions, hospitals, public health and commercial laboratories, biotechnology and pharmaceutical companies, as well as applied laboratories that include food safety and environmental quality. Founded in 1952, Bio-Rad is based in Hercules, California, and has a global network of operations with approximately 8,300 employees worldwide and 2022 revenues of $2.8 billion. For more information, please visit bio-rad.com.

Forward-Looking Statements

This release may be deemed to contain certain forward-looking statements within the meaning of the Private Securities Litigation Reform Act of 1995. These forward-looking statements include, without limitation, statements we make regarding estimated future financial performance or results; the continued underlying strength of our core business in Life Science and Clinical Diagnostics; working diligently through our elevated order backlog to meet customer demand; for the full-year 2023: currently anticipating non-GAAP currency-neutral revenue growth of approximately 4.5 percent, an estimated non-GAAP operating margin of approximately 17.5 percent, and, excluding COVID-related sales, estimating non-GAAP currency-neutral revenue growth of approximately 8.5 percent; and for our 2025 financial outlook: targeting a currency-neutral, compounded annual average core revenue growth rate of approximately 8.0 percent between 2021 and 2025, and an adjusted EBITDA margin of approximately 26.0 percent in 2025. Forward-looking statements generally can be identified by the use of forward-looking terminology such as, “anticipate,” “estimate,” “expect,” “target,” “continue,” “believe,” “will,” “project,” “assume,” “may,” “intend,” or similar expressions or the negative of those terms or expressions, although not all forward-looking statements contain these words. Such statements involve risks and uncertainties, which could cause actual results to vary materially from those expressed in or indicated by the forward-looking statements. These risks and uncertainties include the impact of the COVID-19 pandemic, supply chain issues, global economic conditions, foreign currency exchange fluctuations, our ability to develop and market new or improved products, our ability to compete effectively, reductions in government funding or capital spending of our customers, international legal and regulatory risks, product quality and liability issues, our ability to integrate acquired companies, products or technologies into our company successfully, changes in the healthcare industry, and natural disasters and other catastrophic events beyond our control. For further information regarding the Company’s risks and uncertainties, please refer to the “Risk Factors” and “Management’s Discussion and Analysis of Financial Condition and Results of Operations” in the Company’s public reports filed with the Securities and Exchange Commission (the “SEC”), including the Company’s Annual Report on Form 10-K for the fiscal year ended December 31, 2022, and its Quarterly Report on Form 10-Q for the quarter ended March 31, 2023 to be filed with the SEC. The Company cautions you not to place undue reliance on forward-looking statements, which reflect an analysis only and speak only as of the date hereof. Bio-Rad Laboratories, Inc. disclaims any obligation to update these forward-looking statements.

Bio-Rad Laboratories, Inc.
Condensed Consolidated Statements of Income (Loss)
 
(In thousands, except per share data)
(Unaudited)
 
Three Months Ended
March 31,
 2023  2022 
Net sales$676,844 $700,062 
Cost of goods sold 314,427  297,427 
Gross profit 362,417  402,635 
 
Selling, general and administrative expense 225,553  196,692 
Research and development expense 74,951  59,535 
Income from operations 61,913  146,408 
 
Interest expense 12,337  4,048 
Foreign currency exchange gains, net (2,347) (2,128)
Losses from change in fair market value of equity securities and loan receivable 17,525  4,545,117 
Other income, net (50,431) (32,597)
Income (loss) before income taxes 84,829  (4,368,032)
 
(Provision for) benefit from income taxes (15,867) 1,000,685 
Net income (loss)$68,962 $(3,367,347)
 
Basic earnings (loss) per share:
Net income (loss) per basic share$2.33 $(112.50)
 
Weighted average common shares – basic 29,596  29,933 
 
Diluted earnings (loss) per share:
Net income (loss) per diluted share$2.32 $(112.50)
 
Weighted average common shares – diluted 29,747  29,933
Note:As a result of the net loss for the three months ended March 31, 2022, all potentially issuable common shares have been excluded from the diluted shares used in the computation of earnings per share as their effect was anti-dilutive.
 
Bio-Rad Laboratories, Inc.
Condensed Consolidated Balance Sheets
(In thousands)
 
March 31,December 31,
 2023  2022 
(Unaudited)
Current assets:
Cash and cash equivalents$464,136$434,215
Short-term investments 1,392,877  1,362,017 
Accounts receivable, net 498,273  494,645 
Inventories, net 752,937  719,316 
Other current assets 169,029  147,783 
Total current assets 3,277,252  3,157,976 
 
Property, plant and equipment, net 506,454  498,612 
Operating lease right-of-use assets 174,096  180,952 
Goodwill, net 407,757  406,488 
Purchased intangibles, net 327,828  332,147 
Other investments 8,878,514  8,830,892 
Other assets 95,513  94,599 
Total assets$13,667,414 $13,501,666 
 
Current liabilities:
Accounts payable, accrued payroll and employee benefits$334,892 $329,831 
Current maturities of long-term debt 519  465 
Income and other taxes payable 50,867  32,428 
Other current liabilities 203,345  205,984 
Total current liabilities 589,623  568,708 
 
Long-term debt, net of current maturities 1,198,005  1,197,716 
Other long-term liabilities 2,116,070  2,119,990 
Total liabilities 3,903,698  3,886,414 
 
Total stockholders’ equity 9,763,716  9,615,252 
Total liabilities and stockholders’ equity$13,667,414 $13,501,666 
 
Bio-Rad Laboratories, Inc.
Condensed Consolidated Statements of Cash Flows
(In thousands)
(Unaudited)
 
Three Months Ended
March 31,
 2023  2022 
 
Cash flows from operating activities:
Cash received from customers$677,522 $649,993 
Cash paid to suppliers and employees (552,990) (615,630)
Interest paid, net (22,482) (306)
Income tax payments, net (13,283) (14,324)
Other operating activities 9,352  30,761 
Net cash provided by operating activities 98,119  50,494 
 
Cash flows from investing activities:
Payments for purchases of marketable securities and investments (203,588) (960,940)
Proceeds from sales and maturities of marketable securities and investments 168,840  77,877 
Other investing activities (35,725) (33,078)
Net cash used in investing activities (70,473) (916,141)
 
Cash flows from financing activities:
Proceeds from issuance of Notes, net of debt financing costs   1,186,220 
Payments on long-term borrowings (115) (104)
Other financing activities 4,424  4,177 
Net cash provided by financing activities 4,309  1,190,293 
 
Effect of foreign exchange rate changes on cash (1,996) 6,877 
 
Net increase in cash, cash equivalents and restricted cash 29,959  331,523 
Cash, cash equivalents and restricted cash at beginning of period 434,544  471,133 
Cash, cash equivalents and restricted cash at end of period$464,503 $802,656 
 
 
Reconciliation of net income (loss) to net cash provided by operating activities:
Net income (loss)$68,962 $(3,367,347)
Adjustments to reconcile net income (loss) to net cash provided by operating activities:
Depreciation and amortization 35,587  33,401 
Reduction in the carrying amount of right-of-use assets 9,999  10,018 
Losses from change in fair market value of equity securities and loan receivable 17,525  4,545,117 
Changes in working capital (38,830) (156,678)
Other 4,876  (1,014,017)
Net cash provided by operating activities$98,119 $50,494 
 
Bio-Rad Laboratories, Inc.
Reconciliation of GAAP financial measures to non-GAAP financial measures
(In thousands, except per share data)
(Unaudited)
In addition to the financial measures prepared in accordance with generally accepted accounting principles (GAAP), we use certain non-GAAP financial measures, including non-GAAP net income and non-GAAP diluted income per share (non-GAAP EPS), which exclude amortization of acquisition-related intangible assets; certain acquisition-related expenses and benefits; restructuring charges; asset impairment charges; gains and losses from change in fair market value of equity securities and loan receivable; gains and losses on equity-method investments; and significant legal-related charges or benefits and associated legal costs. Non-GAAP net income and non-GAAP EPS also exclude certain other gains and losses that are either isolated or cannot be expected to occur again with any predictability, tax provisions/benefits related to the previous items, and significant discrete tax events. We exclude the above items because they are outside of our normal operations and/or, in certain cases, are difficult to forecast accurately for future periods.
We utilize a number of different financial measures, both GAAP and non-GAAP, in analyzing and assessing the overall performance of our business, in making operating decisions, forecasting and planning for future periods, and determining payments under compensation programs. We consider the use of the non-GAAP measures to be helpful in assessing the performance of the ongoing operation of our business. We believe that disclosing non-GAAP financial measures provides useful supplemental data that, while not a substitute for financial measures prepared in accordance with GAAP, allows for greater transparency in the review of our financial and operational performance. We also believe that disclosing non-GAAP financial measures provides useful information to investors and others in understanding and evaluating our operating results and future prospects in the same manner as management and in comparing financial results across accounting periods and to those of peer companies.
Three Months EndedThree Months Ended
March 31,% ofMarch 31,% of
 2023 revenue 2022 revenue
 
GAAP cost of goods sold$314,427 $297,427 
Amortization of purchased intangibles (4,288) (4,461)
Restructuring benefits (costs) (330) (3)
Non-GAAP cost of goods sold$309,809 $292,963 
 
GAAP gross profit$362,417 53.5%$402,635 57.5%
Amortization of purchased intangibles 4,288  4,461 
Restructuring (benefits) costs 330  3 
Non-GAAP gross profit$367,035 54.2%$407,099 58.2%
 
GAAP selling, general and administrative expense$225,553 $196,692 
Amortization of purchased intangibles (1,691) (1,849)
Legal matters   (1,193)
Acquisition related benefits (costs) (800)  
Restructuring benefits (costs) (8,988) (144)
Other non-recurring items (2) (1,922) (2,809)
Non-GAAP selling, general and administrative expense$212,152 $190,697 
 
GAAP research and development expense$74,951 $59,535 
Restructuring benefits (costs) (4,235) 103 
Non-GAAP research and development expense$70,716 $59,638 
 
GAAP income from operations$61,913 9.1%$146,408 20.9%
Amortization of purchased intangibles 5,979  6,310 
Legal matters   1,193 
Acquisition related (benefits) costs 800   
Restructuring (benefits) costs 13,553  44 
Other non-recurring items (2) 1,922  2,809 
Non-GAAP income from operations$84,167 12.4%$156,764 22.4%
 
GAAP (gains) losses from change in fair market value of equity securities and loan receivable$17,525 $4,545,117 
Gains (losses) from change in fair market value of equity securities and loan receivable (17,525) (4,545,117)
Non-GAAP (gains) losses from change in fair market value of equity securities and loan receivable$ $ 
 
GAAP other (income) expense, net$(50,431)$(32,597)
Gains (losses) on equity-method investments (995) (990)
Non-GAAP other (income) expense, net$(51,426)$(33,587)
 
GAAP income (loss) before income taxes$84,829 $(4,368,032)
Amortization of purchased intangibles 5,979  6,310 
Legal matters   1,193 
Acquisition related (benefits) costs 800   
Restructuring (benefits) costs 13,553  44 
(Gains) losses from change in fair market value of equity securities and loan receivable 17,525  4,545,117 
(Gains) losses on equity-method investments 995  990 
Other non-recurring items (2) 1,922  2,809 
Non-GAAP income before income taxes$125,603 $188,431 
 
GAAP (provision for) benefit from income taxes$(15,867)$1,000,685 
Income tax effect of non-GAAP adjustments (1) (10,376) (1,037,658)
Non-GAAP provision for income taxes$(26,243)$(36,973)
 
GAAP net income (loss)$68,962 10.2%$(3,367,347)-481.0%
Amortization of purchased intangibles 5,979  6,310 
Legal matters   1,193 
Acquisition related (benefits) costs 800   
Restructuring (benefits) costs 13,553  44 
(Gains) losses from change in fair market value of equity securities and loan receivable 17,525  4,545,117 
(Gains) losses on equity-method investments 995  990 
Other non-recurring items (2) 1,922  2,809 
Income tax effect of non-GAAP adjustments (1) (10,376) (1,037,658)
Non-GAAP net income$99,360 14.7%$151,458 21.6%
 
GAAP diluted income (loss) per share$2.32 $(112.50)
Amortization of purchased intangibles 0.20  0.21 
Legal matters   0.04 
Acquisition related (benefits) costs 0.03   
Restructuring (benefits) costs 0.46   
(Gains) losses from change in fair market value of equity securities and loan receivable 0.59  150.57 
(Gains) losses on equity-method investments 0.03  0.03 
Other non-recurring items (2) 0.06  0.09 
Income tax effect of non-GAAP adjustments (1) (0.35) (34.37)
Add back anti-dilutive shares   0.95 
Non-GAAP diluted income per share$3.34 $5.02 
 
GAAP diluted weighted average shares used in per share calculation 29,747  29,933 
Shares included in non-GAAP net income per share, but excluded from GAAP net loss per share as they would have been anti-dilutive   253 
Non-GAAP diluted weighted average shares used in per share calculation 29,747  30,186 
 
Reconciliation of Net income (loss) to adjusted EBITDA:
GAAP net income (loss)$68,962 10.2%$(3,367,347)-481.0%
Interest expense 12,337  4,048 
(Benefit from) provision for income taxes 15,867  (1,000,685)
Depreciation and amortization 35,587  33,401 
Foreign currency exchange gains, net (2,347) (2,128)
Other income, net (50,431) (32,597)
Losses from change in fair market value of equity securities and loan receivable 17,525  4,545,117 
Dividend from Sartorius AG 34,766  31,586 
Legal matters   1,193 
Acquisition related (benefits) costs 800   
Restructuring (benefits) costs 13,553  44 
Other non-recurring items (2) 1,922  2,809 
Adjusted EBITDA$148,541 21.9%$215,441 30.8%
(1)Excluded items identified in the reconciliation schedule are tax effected by application of a non-GAAP effective tax rate. The non-GAAP tax provision is adjusted for items, the nature of which and/or tax jurisdiction requires the application of a specific tax rate or treatment.
 
(2)Incremental costs to comply with the European Union’s In Vitro Diagnostics Regulation (“IVDR”) for previously approved products.
 
2023 Financial Outlook
 
Forecasted non-GAAP operating margin excludes 80 basis points related to amortization of purchased intangibles. Forecasted non-GAAP operating margin does not reflect future gains and charges that are inherently difficult to predict and estimate due to their unknown timing, effect and/or significance, such as foreign currency fluctuations, future gains or losses associated with certain legal matters, acquisitions and restructuring activities.

Source: https://investors.bio-rad.com/

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