Alcon Launches Clareon PanOptix Pro in Canada: A Breakthrough Trifocal IOL Designed to Minimize Light Scatter

Alcon Launches Clareon PanOptix Pro in Canada: A Breakthrough Trifocal IOL Designed to Minimize Light Scatter

Alcon (SIX/NYSE: ALC), the global eye care leader dedicated to helping people see with clarity, today announced the approval of the Clareon MD PanOptix MD Pro intraocular lens (IOL) for cataract patients in Canada. The PanOptix Pro IOL features ENLIGHTEN MD NXT optics , a proprietary design that provides the lowest light scatter and highest reported light utilization of any trifocal IOL 1-3,5-9,**,‡‡ . PanOptix Pro utilizes 94% of the light, an unprecedented advancement compared to diffractive optics, which have a theoretical maximum utilization of 96% 1-4,*,**,† . These technological advances also enable light distribution with fewer interruptions at both distance and near, and a 16% increase in optical image contrast between distance and intermediate vision 1,‡ ,† † . PanOptix Pro’s reputation is based on its clinically proven low visual disturbance profile, spectacle independence, and exceptionally high patient satisfaction with PanOptix 10-13 lenses,§,§§,¶,¶¶ .

“As a global leader in eye care, we are committed to improving our technologies to deliver better patient outcomes through a rigorous, world-renowned research and development initiative,” said Rob Scott, vice president, intraocular devices, R&D, Alcon. “Our team reviewed hundreds of design options, ultimately settling on a targeted diffractive refinement that helped us recover 50% of the light lost to scatter and reposition it into a favorable focal point for the PanOptix Pro IOL 1,3,10,14-19,* . This allowed for precise improvements while maintaining the features that have led to PanOptix’s success as the world’s most implanted trifocal IOL.” 1-3,20,21,*,**,‡‡,‖,Ω .

“PanOptix has been a mainstay of my cataract specialty practice for eight years now,” said Dr. Rosa Braga-Mele, MD, MEd, FRCSC, Professor, Department of Ophthalmology, University of Toronto. “These lenses have consistently delivered exceptional visual outcomes for my patients 10, 24, § – a low visual disturbance profile 25, ∂ and satisfied patients enjoying greater spectacle independence 23, § . It is therefore exciting to see this technology evolve to better meet patients’ visual expectations. With PanOptix Pro, higher light utilization and lower light scatter is now possible ‡,‡‡ , which is beneficial to both my practice and my patients.”

PanOptix Pro lenses will be available in Canada by Alcon in the single-use Clareon AutonoMe® preloaded delivery system and with the Clareon Monarch® IV delivery system in early 2026. PanOptix Pro offers an intermediate add power of +2.17 diopters and a near add power of +3.25 diopters. Like all Alcon intraocular lenses, PanOptix Pro lenses will be available with blue light and ultraviolet filtering .

For surgeons interested in further information about PanOptix Pro, please contact a local Alcon representative.

About Clareon PanOptix Pro

The Clareon PanOptix Pro Trifocal IOL is a type of multifocal IOL used to focus images clearly on the back of your eye (retina) to enable clear vision after cataract removal. In addition, the center of the Clareon PanOptix Pro Trifocal IOL allows for better near (reading) and intermediate (computer) vision than a monofocal lens would. For indications, precautions, cautions, and warnings, please refer to the individual product’s instructions for use by visiting ifu.alcon.com .

About Alcon

Alcon helps people see clearly. As the global leader in eye care, with a heritage spanning more than 75 years, we offer the broadest range of products to improve sight and lives. Each year, our surgical and eye care products touch the lives of more than 260 million people living with conditions such as cataracts, glaucoma, retinal diseases and refractive errors, in more than 140 countries. Our more than 25,000 associates improve quality of life through innovative products, partnerships with eye care professionals and programs that promote access to quality eye care. Learn more by visiting www.alcon.ca .

*  PanOptix lenses have 88% light utilization (12% light dispersion) and PanOptix Pro lenses have 94% light utilization (6% light dispersion).
**  According to manufacturer reported values ​​and respective methodology for Clareon PanOptix, Envista Envy, AT Elana, Gemetric and Rayner.
†  For diffractive optics achievable up to the pentafocal design of Krackhardt et al .
††  Focus point spread function in simulated photopic vision (light intensity [energy]) – polychromatic.
‡  Compared to Clareon PanOptix.
‡‡  Based on bench and vision simulation studies.
§ Based on a prospective, randomized, multicenter study, at 6 months, a significantly higher number of subjects reported no radiant lights and glare (p < 0.05 n = 276).
§§ Set of analyses of all implantation cases.
¶ Response to the following question on the IOLSAT questionnaire: “During the past 7 days, how often did you have to wear glasses to see?”
¶¶ Response to the following question from the IOLSAT questionnaire (version 1.0, December 20, 2018) 6 months after surgery: “Given your vision today, would you choose the same lens again?”; n = 127.
‖  Based on worldwide unit sales of Clareon PanOptix and AcrySof IQ PanOptix intraocular lenses through Q1 2024.
Ω  Severity ratings of phakic patients who received simulated implantation of PanOptix Pro and Clareon PanOptix using the VirtIOL simulator (n = 64).
∂  Based on a meta-analysis of 11 unique clinical studies involving 580 patients in 10 different countries with “very bothersome” and “severe” visual disturbances. Clinical studies have been conducted on the AcrySof IQ PanOptix IOL; the AcrySof IQ PanOptix and Clareon PanOptix IOLs are optically equivalent.

References

  1. Alcon Internal Data, 2025. REF-25218
  2. Alcon Internal Data, 2024. REF-25221
  3. Alcon Internal Data, 2015. REF-08546
  4. Krackhardt U, et al . Upper bound on the diffraction efficiency of phase-only fanout elements. Applied Optics; 1992; 31:27-37.; 10. Zhu D., Zhang J., et al. Patient-Reported Outcomes of Visual Disturbances with a Trifocal Intraocular Lens: A meta-analysis. Paper presented at the ASCRS Annual Meeting; April 5-8, 2024; Boston.
  5. Muzychuk, A. Defocus Curve Performance of a Novel Hydrophobic Acrylic Trifocal Intraocular Lens: A Prospective, Multicenter Canadian Study. ASCRS Annual Meeting, April 5–8, Boston.
  6. Rayner Professional website. https://rayner.com/en/iol/trifocal/rayone-trifocal/. Accessed September 2024.
  7. Carones F. New concept of Light distribution for bilateral Trifocal IOL implantation. AAO. 2022;2022:53.
  8. ZEISS AT LISA tri family. Supplement in Cataract and Refractive Surgery Today (Europe), septembre 2014.
  9. Zeiss Cataract Insights: Laying the Myth or Reality; Digitalization enhances cataract surgery? Supplement in Ophthalmology Times, Europe; 22 mai 2024; https://europe.ophthalmologytimes.com/zeiss-cataract-insight-series?page=1. Consulté en septembre 2024.
  10. Kohnen T, Lapid-Gortzak R, Ramamurthy D, et al. Clinical outcomes after bilateral implantation of a diffractive trifocal intraocular lens: A worldwide pooled analysis of prospective clinical investigations. Clinical Ophthalmology. 2023;Volume 17:155-163. doi:10.2147/opth.s377234.
  11. Alcon Internal Data, 2024. REF-23958.
  12. Alcon internal data, 2018. REF-01475.
  13. Alcon Vision LLC. Clareon® PanOptix® Trifocal Hydrophobic Acrylic IOL. Product Information. 2021.
  14. Charness N, Dijkstra K, Jastrzembski T, Weaver S, Champion M. Monitor viewing distance for younger and older workers. Proceedings of the Human Factors and Ergonomics Society Annual Meeting. 2008;52(19):1614- 1617. doi:10.1177/154193120805201965
  15. Government of Canada CC for OH and S. CCOHS: Office ergonomics. Canadian Centre for Occupational Health and Safety. 25 avril 2023. Consulté le 9 mai 2023. https://www.ccohs.ca/oshanswers/ergonomics/office/.
  16. Gundersen K, Potvin R. Trifocal intraocular lenses: A comparison of the visual performance and quality of vision provided by two different lens designs. Clinical Ophthalmology. 2017;Volume 11:1081-1087. doi:10.2147/opth.s136164
  17. Kohnen T, Titke C, Böhm M. Trifocal intraocular lens implantation to treat visual demands in various distances following lens removal. American Journal of Ophthalmology. 2016;161. doi:10.1016/j.ajo.2015.09.030
  18. Lwowski C, Pawlowicz K, Petermann K, et al. Visual and patient-reported factors leading to satisfaction after implantation of diffractive extended depth-of-focus and trifocal intraocular lenses. Journal of Cataract and Refractive Surgery. 2022;48(4):421-428. doi:10.1097/j.jcrs.0000000000000780
  19. Alcon Internal Data, 2024. REF-25903
  20. Alcon Internal Data, 2024. REF-23554
  21. MarketScope LLC. 2023 IOL Market Report: Global Analysis for 2022 to 2028. St. Louis, MO: MarketScope LLC; 2023.
  22. Clareon® PanOptix® Pro Trifocal Hydrophobic Acrylic IOL Model PXYWT0 2024 Directions for Use.
  23. Zhu D, et al. Rate of complete spectacle independence with a trifocal intraocular lens: A systematic literature review and meta-analysis. Ophthalmology and Therapy. 2023;12(2):1157-1171. doi:10.1007/s40123-023-00657-5.Alcon Vision LLC.
  24. Modi S, Lehmann R, Maxwell A, et al. Visual and patient-reported outcomes of a diffractive trifocal intraocular lens compared with those of a monofocal intraocular lens. Ophthalmology. 2021;128(2):197-207. doi:10.1016/j.ophtha.2020.07.015
  25. Zhu D., Zhang J., et al . Patient-Reported Outcomes of Visual Disturbances with a Trifocal Intraocular Lens: A Meta-Analysis. Paper presented at the ASCRS Annual Meeting; April 5-8, 2024; Boston.

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