Galderma, a global leader in dermatology, is pioneering research into the effects of medication-driven weight loss on the skin and the importance of incorporating aesthetic treatments into the patient journey. As the prevalence of prescription weight loss medications grows, with projected global sales expected to reach $100 billion by 2030, the impact on aesthetics is becoming increasingly significant for both patients and healthcare professionals.
Addressing Facial Volume Loss in Weight Loss Patients
During the International Master Course on Aging Science (IMCAS) 2025 annual congress, Galderma is hosting an exclusive masterclass titled “Managing Facial Changes in Patients with Medication-Driven Weight Loss.” This session will bring together international aesthetics experts to discuss strategies for addressing the unique facial transformations experienced by patients using weight loss medications.
Rapid weight loss can lead to substantial changes in facial volume and structure, resulting in issues such as sagging skin, loss of facial balance, and a hollowed appearance. Research indicates that nearly 48% of individuals using weight loss medications report significant facial changes. These effects are particularly pronounced in menopausal women, who are more likely to experience sagging, loss of skin radiance, and a slimmer facial profile.
The First International Consensus-Based Guidelines
Recognizing the widespread impact of medication-driven weight loss on aesthetics, Galderma initiated the Delphi study to develop global, evidence-based guidelines for treating this unique patient population. The study incorporated patient interviews, market research, literature reviews, and expert insights to establish best practices for managing facial changes resulting from rapid weight loss.
Dr. Andreas Nikolis will present these novel consensus guidelines during a dedicated focus session titled “Rapid Facial Volume Loss: Causes and Consequences” on January 31, 2025, at the Grand Amphi. These guidelines will offer healthcare professionals a structured approach to identifying and addressing aesthetic concerns in patients undergoing medication-induced weight loss.
In addition to this research, Galderma has conducted a large-scale survey of over 1,000 individuals aged 25-65 across the United States, Brazil, Europe, and the Middle East. This study aimed to enhance the understanding of how weight loss medications affect skin quality and facial aesthetics, equipping healthcare professionals with the knowledge needed to offer informed recommendations.
Growing Demand for Aesthetic Treatments
As weight loss medications become more widely used, a new patient demographic is emerging—individuals who have achieved significant weight loss and are now seeking complementary aesthetic treatments. Research shows that 62% of patients using GLP-1 weight loss medications pursue aesthetic treatments following a recommendation from a healthcare professional.
According to survey data:
- 60% of aesthetic users have undergone treatments to address skin changes due to weight loss.
- One-third of aesthetic treatment considerers would have taken preventive measures if they had been aware of potential skin changes before starting their weight loss journey.
- Over 60% of patients expressed interest in an integrated approach that combines medical and aesthetic expertise to support them through their transformation.
Despite the increasing interest in aesthetic solutions, a lack of education and information remains a significant barrier to treatment. Many patients are unaware of the potential effects of weight loss medications on their skin, underscoring the need for increased awareness and guidance from healthcare professionals.
A Holistic Approach to Aesthetic Care
Dr. Andreas Nikolis emphasizes the importance of a comprehensive, patient-centered approach in addressing these changes:
With 23% of patients planning to undergo aesthetic treatments, we are witnessing the rise of a distinct patient population—those seeking to enhance their transformation post-weight loss. These patients require a thoughtful, integrated approach from healthcare providers. Galderma’s cutting-edge research equips healthcare professionals with the insights needed to address this shift. By prioritizing a holistic, personalized strategy, we can optimize both physical appearance and overall well-being.”
Facial changes following weight loss occur due to several factors, including fat loss, decreased collagen and elastin production, and diminished skin hydration. The depletion of subcutaneous fat, which provides structure and youthful volume, often leads to facial sagging and loss of definition. The reduction of essential nutrients further contributes to decreased skin elasticity and a lackluster complexion.
To address these challenges, aesthetic treatments such as dermal fillers and collagen-stimulating injectables have gained popularity. Among survey respondents:
- 48% expressed interest in Sculptra® treatments to restore facial volume and improve skin texture.
- 41% considered Restylane® to enhance facial contours and rejuvenate their appearance.
These findings highlight the demand for advanced, individualized aesthetic treatments tailored to the specific needs of weight loss patients.
Galderma’s Commitment to Dermatological Innovation
Gerry Muhle, Head of Global Product Strategy at Galderma, underscores the company’s dedication to addressing the evolving needs of patients undergoing weight loss:
Galderma is committed to leading the way in understanding the impact of medication-driven weight loss on the skin. As the dermatology category leader, we recognize that there is no one-size-fits-all approach. With our deep expertise in skin science, aesthetics, and personalized treatment strategies, we are uniquely positioned to help patients achieve their desired appearance and maintain healthy, radiant skin.”
By leveraging its extensive dermatological expertise, Galderma is shaping the future of aesthetic medicine. Through ongoing research, expert collaborations, and the development of evidence-based guidelines, the company is empowering healthcare professionals to provide comprehensive, tailored solutions that enhance both physical transformation and overall confidence.
As the landscape of weight loss treatments evolves, so too must the approach to aesthetic care. By integrating medical and aesthetic expertise, patients can achieve holistic, long-lasting results that support their weight loss journey while maintaining youthful, healthy skin.
