Genome Insight to Unveil Hong Kong Real-World Evidence on Target Enhanced Whole Genome Sequencing at 2023 AACR-KCA Joint Conference
Genome Insight, a precision healthcare solutions company advancing whole-genome technology for accurate diagnosis and personalized treatment for cancer and rare disease, will announce new-real-world evidence from Hong Kong on the application of Target Enhanced Whole Genome Sequencing (TE-WGS) at the 2023 AACR-KCA joint conference on Precision Medicine in Cancer in Seoul, Korea.
Genome Insight’s presentation will feature the outcomes of a collaborative real-world evidence program on TE-WGS in lung cancers. The program focused on non-small cell lung adenocarcinoma and drew on a TE-WGS pipeline exclusively designed for solid tumors, known as CancerVision.
The presentation will highlight a case that underscores the importance of adopting a comprehensive TE-WGS genomic assessment strategy, relative to the current practice of serial panel testing. Genome Insight will present the case of a 78-year-old Asian man from Hong Kong with poorly differentiated Non-Small Cell Lung Cancer (NSCLC). The patient underwent multiple lines of standard treatment before the identification of actionable biomarkers through TE-WGS.
The results indicated that CancerVision was able to detect actionable biomarkers, including MET gene amplification with a Gene Copy Number (GCN) of 8, a high TMB of 14.88 muts/mb, and a tobacco-smoking-induced whole-genome sequencing signature. These biomarkers had not been identified previously through conventional NGS panel testing methods.
“We are thrilled to present this real-world evidence from Hong Kong at the esteemed 2023 AACR-KCA Joint Conference,” said Ryul Kim, Chief Technology Officer. “Genome Insight is committed to advancing precision oncology through innovative, collaborative research projects like this one. We believe that TE-WGS is a powerful tool for improving the precision and speed of therapeutic decision-making and look forward to sharing our findings with the global community.
